She is the host of the podcast Honestly, and is the winner of the LA Press Club's 2021 Daniel Pearl Award for Courage and Integrity in Journalism. She is also the winner of the Reason Foundation’s 2018 Bastiat Prize, which honors writing that “best demonstrates the importance of freedom with originality, wit, and eloquence.” In 2019, Vanity Fair called Weiss the Times's "star opinion writer." In 2023, Weiss and The Free Press won the Dao Prize for their work on the Twitter Files.
Weiss is a proud Pittsburgh native. Her first book, "How to Fight Anti-Semitism," was the winner of a 2019 National Jewish Book Award. She lives with her wife and daughter in Los Angeles.